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Vasculature visualization by the differential method

19960118_Vasulature visualization by the differential method

Initial demonstration of the differential method


Resultant composite images from application of the differential method


Infrared Imaging for localization of angiogenic processes


Non-invasive visualization of the veinous tree in the human breast without any contrast media by the differential method


non-invasive visualization of serpentine veins by the differential method


Non-invasive visualization ov the angiogenesis process by the differential method


19970922_comparison of images obtained by he differential methods


19990509_non-invasive identification of breast cancer

Method and apparatus for high resolution dynamic digital infrared imaging: The Differential Method

United States Patent 8,233,968

USPTO Abstract:

An infrared imaging camera (4) acquires a plurality of frames (94) of infrared radiation from a patient (P) positioned in a field-of-view (92) of the camera (4). Each frame (94) is acquired during a corresponding frame sample interval and each frame (94) corresponds to the infrared radiation acquired from an array of optical elements (90) in the field-of-view (92) during its frame sample interval. Plural rates of change are determined from infrared radiation received from the array of optical elements (90), with each rate of change corresponding to a change of infrared radiation received from the same optical element (90) in at least two frames (94). Each rate of change is mapped to a color or a shade of gray and the color or shade of gray of each rate of change is mapped to a position in an image corresponding to the position of the corresponding optical element (90) in the field-of-view (92). The camera (4) can be used for early detection of neoplastic disease process, detection of angiogenesis and/or identification of treatment sites for pain management therapeutic modalities.

You may access and download as a pdf the United States Patent 8233968 and acess and download as a pdf the French text of the Canadian Patent, Procede et dispositif dynamique d’imagerie infrarouge numerique haute resolution